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Ndufaf5 deficiency in the Dictyostelium model: new roles in autophagy and development

Ndufaf5 (also known as C20orf7) is a mitochondrial complex I (CI) assembly factor whose mutations lead to human mitochondrial disease. Little is known about the function of the protein and the cytopathological consequences of the mutations. Disruption of Dictyostelium Ndufaf5 leads to CI deficiency...

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Detalles Bibliográficos
Autores principales: Carilla-Latorre, Sergio, Annesley, Sarah J., Muñoz-Braceras, Sandra, Fisher, Paul R., Escalante, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655813/
https://www.ncbi.nlm.nih.gov/pubmed/23536703
http://dx.doi.org/10.1091/mbc.E12-11-0796