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Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans

Efficient clearance of apoptotic cells by phagocytes is important for development, tissue homeostasis, and the prevention of autoimmune responses. Phagosomes containing apoptotic cells undergo acidification and mature from Rab5-positive early to Rab7-positive late stages. Phagosomes finally fuse wit...

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Detalles Bibliográficos
Autores principales: Sasaki, Ayaka, Nakae, Isei, Nagasawa, Maya, Hashimoto, Keisuke, Abe, Fumiko, Saito, Kota, Fukuyama, Masamitsu, Gengyo-Ando, Keiko, Mitani, Shohei, Katada, Toshiaki, Kontani, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655818/
https://www.ncbi.nlm.nih.gov/pubmed/23485564
http://dx.doi.org/10.1091/mbc.E12-08-0628