A human Dravet syndrome model from patient induced pluripotent stem cells

BACKGROUND: Dravet syndrome is a devastating infantile-onset epilepsy syndrome with cognitive deficits and autistic traits caused by genetic alterations in SCN1A gene encoding the α-subunit of the voltage-gated sodium channel Na(v)1.1. Disease modeling using patient-derived induced pluripotent stem...

Descripción completa

Detalles Bibliográficos
Autores principales: Higurashi, Norimichi, Uchida, Taku, Lossin, Christoph, Misumi, Yoshio, Okada, Yohei, Akamatsu, Wado, Imaizumi, Yoichi, Zhang, Bo, Nabeshima, Kazuki, Mori, Masayuki X, Katsurabayashi, Shutaro, Shirasaka, Yukiyoshi, Okano, Hideyuki, Hirose, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655893/
https://www.ncbi.nlm.nih.gov/pubmed/23639079
http://dx.doi.org/10.1186/1756-6606-6-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655893/
https://www.ncbi.nlm.nih.gov/pubmed/23639079
http://dx.doi.org/10.1186/1756-6606-6-19

Ejemplares similares