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Stochastic Model of Tsc1 Lesions in Mouse Brain

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder due to mutations in either TSC1 or TSC2 that affects many organs with hamartomas and tumors. TSC-associated brain lesions include subependymal nodules, subependymal giant cell astrocytomas and tubers. Neurologic manifestations in TSC...

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Detalles Bibliográficos
Autores principales: Prabhakar, Shilpa, Goto, June, Zuang, Xuan, Sena-Esteves, Miguel, Bronson, Roderick, Brockmann, Jillian, Gianni, Davide, Wojtkiewicz, Gregory R., Chen, John W., Stemmer-Rachamimov, Anat, Kwiatkowski, David J., Breakefield, Xandra O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655945/
https://www.ncbi.nlm.nih.gov/pubmed/23696872
http://dx.doi.org/10.1371/journal.pone.0064224