Increased Polyamine Intake Inhibits Age-Associated Alteration in Global DNA Methylation and 1,2-Dimethylhydrazine-Induced Tumorigenesis

Polyamines (spermine and spermidine) play many important roles in cellular function and are supplied from the intestinal lumen. We have shown that continuous high polyamine intake inhibits age-associated pathologies in mice. The mechanism by which polyamines elicit these effects was examined. Twenty...

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Detalles Bibliográficos
Autores principales: Soda, Kuniyasu, Kano, Yoshihiko, Chiba, Fumihiro, Koizumi, Kei, Miyaki, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655973/
https://www.ncbi.nlm.nih.gov/pubmed/23696883
http://dx.doi.org/10.1371/journal.pone.0064357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655973/
https://www.ncbi.nlm.nih.gov/pubmed/23696883
http://dx.doi.org/10.1371/journal.pone.0064357

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