Interferon-λ1 Linked to a Stabilized Dimer of Fab Potently Enhances both Antitumor and Antiviral Activities in Targeted Cells

The type III interferons (IFNs), comprising IFN-λ1, IFN-λ2, and IFN-λ3, behave similarly to IFN-α in eliciting antiviral, antitumor, and immune-modulating activities. Due to their more restricted cellular targets, IFN-λs are attractive as potential alternatives to existing therapeutic regimens based...

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Detalles Bibliográficos
Autores principales: Liu, Donglin, Chang, Chien-Hsing, Rossi, Edmund A., Cardillo, Thomas M., Goldenberg, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655979/
https://www.ncbi.nlm.nih.gov/pubmed/23696859
http://dx.doi.org/10.1371/journal.pone.0063940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655979/
https://www.ncbi.nlm.nih.gov/pubmed/23696859
http://dx.doi.org/10.1371/journal.pone.0063940

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