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Monoallelic Chromatin Conformation Flanking Long-Range Silenced Domains in Cancer-Derived and Normal Cells

Epigenetic inactivation of chromatin plays an important role in determining cell phenotype in both normal and cancer cells, but our knowledge is still incomplete with respect to any potential monoallelic nature of the phenomenon. We have genotyped DNA isolated from chromatin of two colorectal cancer...

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Detalles Bibliográficos
Autores principales: Di Paola, Domenic, Raelson, John, Rampakakis, Emmanouil, Basik, Mark, Zannis-Hadjopoulos, Maria, Bradley, W. Edward C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655995/
https://www.ncbi.nlm.nih.gov/pubmed/23696799
http://dx.doi.org/10.1371/journal.pone.0063190