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Neurotoxic phospholipase A(2) toxicity model: An insight from mammalian cells

The molecular mechanism of action of presynaptically neurotoxic secreted phospholipases A(2) (sPLA(2)s) has not been fully elucidated. We have recently proposed a model to explain one of the hallmarks of their action – the reduction in endocytosis leading to synaptic vesicle depletion in nerve termi...

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Detalles Bibliográficos
Autores principales: Vardjan, Nina, Mattiazzi, Mojca, Rowan, Edward G., Križaj, Igor, Petrovič, Uroš, Petan, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656009/
https://www.ncbi.nlm.nih.gov/pubmed/23710275
http://dx.doi.org/10.4161/cib.23600