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SAP97 Controls the Trafficking and Resensitization of the Beta-1-Adrenergic Receptor through Its PDZ2 and I3 Domains

Previous studies have determined that the type-1 PDZ sequence at the extreme carboxy-terminus of the ß(1)-adrenergic receptor (ß(1)-AR) binds SAP97 and AKAP79 to organize a scaffold involved in trafficking of the ß(1)-AR. In this study we focused on characterizing the domains in SAP97 that were invo...

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Detalles Bibliográficos
Autores principales: Nooh, Mohammed M., Naren, Anjaparavanda P., Kim, Sung-Jin, Xiang, Yang K., Bahouth, Suleiman W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656048/
https://www.ncbi.nlm.nih.gov/pubmed/23696820
http://dx.doi.org/10.1371/journal.pone.0063379