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APC(CDH1) Targets MgcRacGAP for Destruction in the Late M Phase

BACKGROUND: Male germ cell RacGTPase activating protein (MgcRacGAP) is an important regulator of the Rho family GTPases — RhoA, Rac1, and Cdc42 — and is indispensable in cytokinesis and cell cycle progression. Inactivation of RhoA by phosphorylated MgcRacGAP is an essential step in cytokinesis. MgcR...

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Detalles Bibliográficos
Autores principales: Nishimura, Koutarou, Oki, Toshihiko, Kitaura, Jiro, Kuninaka, Shinji, Saya, Hideyuki, Sakaue-Sawano, Asako, Miyawaki, Atsushi, Kitamura, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656054/
https://www.ncbi.nlm.nih.gov/pubmed/23696789
http://dx.doi.org/10.1371/journal.pone.0063001