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APC(CDH1) Targets MgcRacGAP for Destruction in the Late M Phase
BACKGROUND: Male germ cell RacGTPase activating protein (MgcRacGAP) is an important regulator of the Rho family GTPases — RhoA, Rac1, and Cdc42 — and is indispensable in cytokinesis and cell cycle progression. Inactivation of RhoA by phosphorylated MgcRacGAP is an essential step in cytokinesis. MgcR...
Autores principales: | Nishimura, Koutarou, Oki, Toshihiko, Kitaura, Jiro, Kuninaka, Shinji, Saya, Hideyuki, Sakaue-Sawano, Asako, Miyawaki, Atsushi, Kitamura, Toshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656054/ https://www.ncbi.nlm.nih.gov/pubmed/23696789 http://dx.doi.org/10.1371/journal.pone.0063001 |
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