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Highly Upregulated Lhx2 in the Foxn1(−/−) Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche

Hair cycling is a prime example of stem cell dependent tissue regeneration and replenishment, and its regulatory mechanisms remain poorly understood. In the present study, we evaluated the effect of a blockage in terminal keratinocytic lineage differentiation in the Foxn1(−/−) nude phenotype on the...

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Detalles Bibliográficos
Autores principales: Bohr, Stefan, Patel, Suraj J., Vasko, Radovan, Shen, Keyue, Huang, Guofeng, Yarmush, Martin L., Berthiaume, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656088/
https://www.ncbi.nlm.nih.gov/pubmed/23696871
http://dx.doi.org/10.1371/journal.pone.0064223