IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection

Foxp3(+) regulatory T (Treg) cells are essential for the maintenance of immune homeostasis and tolerance. During viral infections, Treg cells can limit the immunopathology resulting from excessive inflammation, yet potentially inhibit effective antiviral T cell responses and promote virus persistenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmitz, Iwana, Schneider, Christoph, Fröhlich, Anja, Frebel, Helge, Christ, Daniel, Leonard, Warren J., Sparwasser, Tim, Oxenius, Annette, Freigang, Stefan, Kopf, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656089/
https://www.ncbi.nlm.nih.gov/pubmed/23696736
http://dx.doi.org/10.1371/journal.ppat.1003362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656089/
https://www.ncbi.nlm.nih.gov/pubmed/23696736
http://dx.doi.org/10.1371/journal.ppat.1003362

Ejemplares similares