Cargando…

Saturated Very Long Chain Fatty Acids Are Required for the Production of Infectious Human Cytomegalovirus Progeny

Human cytomegalovirus hijacks host cell metabolism, increasing the flux of carbon from glucose to malonyl-CoA, the committed precursor to fatty acid synthesis and elongation. Inhibition of acetyl-CoA carboxylase blocks the production of progeny virus. To probe further the role of fatty acid metaboli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koyuncu, Emre, Purdy, John G., Rabinowitz, Joshua D., Shenk, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656100/ https://www.ncbi.nlm.nih.gov/pubmed/23696731 http://dx.doi.org/10.1371/journal.ppat.1003333

Ejemplares similares

Fatty Acid Elongase 7 Catalyzes the Lipidome Remodeling Essential for Human Cytomegalovirus Replication
por: Purdy, John G., et al.
Publicado: (2015)

Human Cytomegalovirus Uses a Host Stress Response To Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very-Long-Chain Fatty Acids
por: Xi, Yuecheng, et al.
Publicado: (2021)

Divergent Effects of Human Cytomegalovirus and Herpes Simplex Virus-1 on Cellular Metabolism
por: Vastag, Livia, et al.
Publicado: (2011)

Very long-chain saturated fatty acids and diabetes and cardiovascular disease
por: Lemaitre, Rozenn N., et al.
Publicado: (2022)

Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness
por: Zierfuss, Bettina, et al.
Publicado: (2022)

Genetic loci associated with circulating levels of very long-chain saturated fatty acids
por: Lemaitre, Rozenn N., et al.
Publicado: (2015)

Serum Saturated Fatty Acids including Very Long-Chain Saturated Fatty Acids and Colorectal Cancer Risk among Chinese Population
por: Wu, Qixin, et al.
Publicado: (2023)

Circulating Very Long‐Chain Saturated Fatty Acids and Heart Failure: The Cardiovascular Health Study
por: Lemaitre, Rozenn N., et al.
Publicado: (2018)

Intracellular Staphylococcus aureus Elicits the Production of Host Very Long-Chain Saturated Fatty Acids with Antimicrobial Activity
por: Bravo-Santano, Natalia, et al.
Publicado: (2019)

Saturated very long chain fatty acid configures glycosphingolipid for lysosome homeostasis in long-lived C. elegans
por: Wang, Feng, et al.
Publicado: (2021)

Dynamics of the Cellular Metabolome during Human Cytomegalovirus Infection
por: Munger, Joshua, et al.
Publicado: (2006)

Dysregulation of very-long-chain fatty acid metabolism causes membrane saturation and induction of the unfolded protein response
por: Micoogullari, Yagmur, et al.
Publicado: (2020)

Phs1 and the Synthesis of Very Long Chain Fatty Acids Are Required for Ballistospore Formation
por: Ianiri, Giuseppe, et al.
Publicado: (2014)

Low Circulating Concentrations of Very Long Chain Saturated Fatty Acids Are Associated with High Risk of Mortality in Kidney Transplant Recipients
por: Vogelpohl, Fabian A., et al.
Publicado: (2021)

Lifestyle Factors Associated with Circulating Very Long-Chain Saturated Fatty Acids in Humans: A Systematic Review of Observational Studies
por: Lai, Kira Zhi Hua, et al.
Publicado: (2022)

Enhanced production of nitric oxide, reactive oxygen species, and pro-inflammatory cytokines in very long chain saturated fatty acid-accumulated macrophages
por: Yanagisawa, Naotake, et al.
Publicado: (2008)

Human Cytomegalovirus Tegument Protein pUL71 Is Required for Efficient Virion Egress
por: Womack, Andrew, et al.
Publicado: (2010)

Enhancing very long chain fatty acids production in Yarrowia lipolytica
por: Gajdoš, Peter, et al.
Publicado: (2022)

Requirement of GrgA for Chlamydia infectious progeny production, optimal growth, and efficient plasmid maintenance
por: Lu, Bin, et al.
Publicado: (2023)

Dietary Very Long Chain Saturated Fatty Acids and Metabolic Factors: Findings from the Korea National Health and Nutrition Examination Survey 2013
por: Lee, Youn Sue, et al.
Publicado: (2015)

Circulating Very-Long-Chain Saturated Fatty Acids Were Inversely Associated with Cardiovascular Health: A Prospective Cohort Study and Meta-Analysis
por: Liu, Meng, et al.
Publicado: (2020)

Metabolism of Very Long-Chain Fatty Acids: Genes and Pathophysiology
por: Sassa, Takayuki, et al.
Publicado: (2014)

Fatty acid transport protein 4 is required for incorporation of saturated ultralong-chain fatty acids into epidermal ceramides and monoacylglycerols
por: Lin, Meei-Hua, et al.
Publicado: (2019)

Algae: Critical Sources of Very Long-Chain Polyunsaturated Fatty Acids
por: Harwood, John L.
Publicado: (2019)

Saturated long-chain fatty acid-producing bacteria contribute to enhanced colonic motility in rats
por: Zhao, Ling, et al.
Publicado: (2018)

Long-Chain Saturated Fatty Acids, Palmitic and Stearic Acids, Enhance the Repair of Photosystem II
por: Jimbo, Haruhiko, et al.
Publicado: (2020)

Central Regulation of Brown Fat Thermogenesis in Response to Saturated or Unsaturated Long-Chain Fatty Acids
por: Fosch, Anna, et al.
Publicado: (2023)

Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals
por: Yu, Tao, et al.
Publicado: (2017)

Assembly of infectious Kaposi’s sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer
por: Naniima, Peter, et al.
Publicado: (2021)

High contents of very long-chain polyunsaturated fatty acids in different moss species
por: Beike, Anna K., et al.
Publicado: (2013)

How Very-Long-Chain Fatty Acids Could Signal Stressful Conditions in Plants?
por: De Bigault Du Granrut, Antoine, et al.
Publicado: (2016)

Glycosphingolipids with Very Long-Chain Fatty Acids Accumulate in Fibroblasts from Adrenoleukodystrophy Patients
por: Fujiwara, Yuko, et al.
Publicado: (2021)

Defects in Very Long-Chain Fatty Acid Oxidation Presenting as Different Types of Cardiomyopathy
por: Alaei, Fariba, et al.
Publicado: (2022)

Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation
por: Hammer, Anna, et al.
Publicado: (2017)

Differential routing and disposition of the long-chain saturated fatty acid palmitate in rodent vs human beta-cells
por: Thomas, Patricia, et al.
Publicado: (2022)

Author Correction: Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals
por: Yu, Tao, et al.
Publicado: (2018)

Subviral Dense Bodies of Human Cytomegalovirus Enhance Interferon-Beta Responses in Infected Cells and Impair Progeny Production
por: Penner, Inessa, et al.
Publicado: (2023)

The Small Molecule H89 Inhibits Chlamydia Inclusion Growth and Production of Infectious Progeny
por: Muñoz, Karissa J., et al.
Publicado: (2021)

Lactones from Unspecific Peroxygenase-Catalyzed In-Chain Hydroxylation of Saturated Fatty Acids
por: Ebrecht, Ana C., et al.
Publicado: (2023)

The role of ELOVL1 in very long-chain fatty acid homeostasis and X-linked adrenoleukodystrophy
por: Ofman, Rob, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_6pd3m0lqmvlgvgj08vhrb86d4c