Cargando…

Succinate Dehydrogenase Deficiency in Pediatric and Adult Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) in adults are generally driven by somatic gain-of-function mutations in KIT or PDGFRA, and biological therapies targeted to these receptor tyrosine kinases comprise part of the treatment regimen for metastatic and inoperable GISTs. A minority (10–15%) of GISTs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belinsky, Martin G., Rink, Lori, von Mehren, Margaret
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656383/ https://www.ncbi.nlm.nih.gov/pubmed/23730622 http://dx.doi.org/10.3389/fonc.2013.00117

Ejemplares similares

Succinate dehydrogenase deficiency in a PDGFRA mutated GIST
por: Belinsky, Martin G., et al.
Publicado: (2017)

Role of succinate dehydrogenase deficiency and oncometabolites in gastrointestinal stromal tumors
por: Zhao, Yue, et al.
Publicado: (2020)

Advances and Challenges on Management of Gastrointestinal Stromal Tumors
por: Mei, Lin, et al.
Publicado: (2018)

ZNF-Mediated Resistance to Imatinib Mesylate in Gastrointestinal Stromal Tumor
por: Rink, Lori, et al.
Publicado: (2013)

Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumors: Small Steps Toward Personalized Medicine?
por: Ravegnini, Gloria, et al.
Publicado: (2019)

Early and Next-Generation KIT/PDGFRA Kinase Inhibitors and the Future of Treatment for Advanced Gastrointestinal Stromal Tumor
por: Bauer, Sebastian, et al.
Publicado: (2021)

Clinicopathologic study of succinate-dehydrogenase-deficient gastrointestinal stromal tumors: A single-institutional experience in China
por: Liu, Weizhen, et al.
Publicado: (2017)

Combined Inhibition of AKT and KIT Restores Expression of Programmed Cell Death 4 (PDCD4) in Gastrointestinal Stromal Tumor
por: Kozinova, Marya, et al.
Publicado: (2021)

Identification of Wee1 as a target in combination with avapritinib for gastrointestinal stromal tumor treatment
por: Ye, Shuai, et al.
Publicado: (2021)

Succinate dehydrogenase deficient renal cell carcinoma: A case report
por: Kumar, Raj A., et al.
Publicado: (2021)

Succinate dehydrogenase-deficient gastrointestinal stromal tumor: from diagnostic dilemma to novel personalised therapy in 2 case reports
por: De Silva, Madhawa, et al.
Publicado: (2021)

Succinate dehydrogenase‐deficient malignant paraganglioma complicated by succinate dehydrogenase‐deficient renal cell carcinoma
por: Yamaguchi, Yoshitomo, et al.
Publicado: (2022)

Succinic Semialdehyde Dehydrogenase Deficiency: An Update
por: Didiasova, Miroslava, et al.
Publicado: (2020)

An unusual site of metastasis from gastrointestinal stromal tumor
por: Cauchi, Carolina, et al.
Publicado: (2010)

Succinate dehydrogenase deficient gastrointestinal stromal tumor in a three month old boy with a fatal clinical course: a case report and review of literature
por: Lv, Bei-Bei, et al.
Publicado: (2021)

Succinate Dehydrogenase Deficiency Is Rare in Pituitary Adenomas
por: Gill, Anthony J., et al.
Publicado: (2014)

Gastrointestinal Stromal Tumors: Deception to the Eyesight
por: Haddad, Fady G., et al.
Publicado: (2017)

Somatic loss of function mutations in neurofibromin 1 and MYC associated factor X genes identified by exome-wide sequencing in a wild-type GIST case
por: Belinsky, Martin G., et al.
Publicado: (2015)

Cardiac‐specific succinate dehydrogenase deficiency in Barth syndrome
por: Dudek, Jan, et al.
Publicado: (2015)

Rapamycin as a potential treatment for succinate dehydrogenase deficiency
por: Fan, Frances, et al.
Publicado: (2019)

Succinate Dehydrogenase Deficiency: A Treatable Neurometabolic Disorder
por: KARIMZADEH, Parvaneh, et al.
Publicado: (2020)

Succinic semialdehyde dehydrogenase deficiency presenting with central hypothyroidism
por: Alghamdi, Malak Ali, et al.
Publicado: (2020)

SDHA Germline Variants in Adult Patients With SDHA-Mutant Gastrointestinal Stromal Tumor
por: Pantaleo, Maria A., et al.
Publicado: (2022)

Apatinib Treatment in Metastatic Gastrointestinal Stromal Tumor
por: Cai, Zhaolun, et al.
Publicado: (2019)

Imaging findings of succinate dehydrogenase‐deficient renal cell carcinoma
por: Liu, Wenqin, et al.
Publicado: (2023)

Succinate Dehydrogenase Subunit B (SDHB) Is Expressed in Neurofibromatosis 1-Associated Gastrointestinal Stromal Tumors (Gists): Implications for the SDHB Expression Based Classification of Gists
por: Wang, Jeanny H., et al.
Publicado: (2011)

De novo dedifferentiated SDH-deficient gastrointestinal stromal tumor with MDM2 amplification: case report and literature review
por: Gong, Qi-Xing, et al.
Publicado: (2023)

Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas
por: Matlac, Dieter M., et al.
Publicado: (2021)

An overview of agents and treatments for PDGFRA-mutated gastrointestinal stromal tumors
por: Sun, Yingchao, et al.
Publicado: (2022)

Expression levels of insulin-like growth factors and receptors in hepatocellular carcinoma: a retrospective study
por: Chun, Yun Shin, et al.
Publicado: (2014)

Evidence of redox imbalance in a patient with succinic semialdehyde dehydrogenase deficiency
por: Niemi, Anna-Kaisa, et al.
Publicado: (2014)

Aberrant Splicing of SDHC in Families With Unexplained Succinate Dehydrogenase-Deficient Paragangliomas
por: De Sousa, Sunita M C, et al.
Publicado: (2020)

KIT mutation in a naïve succinate dehydrogenase‐deficient gastric GIST
por: Brcic, Iva, et al.
Publicado: (2019)

Sensorineural Hearing Loss in a Child with Succinic Semialdehyde Dehydrogenase Deficiency
por: Parezanović, M, et al.
Publicado: (2023)

Succinic Dehydrogenase and Cytochrome Oxidase Activities in Cell Cultures
por: Leslie, I., et al.
Publicado: (1960)

Adolescent male with bilateral succinate dehydrogenase-deficient renal cell carcinoma in a horseshoe kidney managed successfully with staged bilateral robotic-assisted partial nephrectomies: A case report
por: Pulford, Christopher, et al.
Publicado: (2023)

p53 as a biomarker and potential target in gastrointestinal stromal tumors
por: Wu, Chiao-En, et al.
Publicado: (2022)

Advances in the research of the mechanism of secondary resistance to imatinib in gastrointestinal stromal tumors
por: Hu, Xiangchen, et al.
Publicado: (2022)

Role of Surgery in the Management of Liver Metastases From Gastrointestinal Stromal Tumors
por: Xue, Anwei, et al.
Publicado: (2022)

The Role of Endoscopy in the Diagnosis of Gastric Gastrointestinal Stromal Tumors
por: Nishida, Toshirou
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_d8of418heiieqttrbdc7o0pblm