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Clinical Grade Purification and Expansion of NK Cell Products for an Optimized Manufacturing Protocol

Allogeneic natural killer (NK) cells are used for adoptive immunotherapy after stem cell transplantation. In order to overcome technical limitations in NK cell purification and activation, the following study investigates the impact of different variables on NK cell recovery, cytotoxicity, and T-cel...

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Detalles Bibliográficos
Autores principales: Koehl, Ulrike, Brehm, Claudia, Huenecke, Sabine, Zimmermann, Stefanie-Yvonne, Kloess, Stephan, Bremm, Melanie, Ullrich, Evelyn, Soerensen, Jan, Quaiser, Andrea, Erben, Stephanie, Wunram, Claudia, Gardlowski, Tanja, Auth, Eileen, Tonn, Torsten, Seidl, Christian, Meyer-Monard, Sandrine, Stern, Martin, Passweg, Jakob, Klingebiel, Thomas, Bader, Peter, Schwabe, Dirk, Esser, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656406/
https://www.ncbi.nlm.nih.gov/pubmed/23730623
http://dx.doi.org/10.3389/fonc.2013.00118