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Evaluation of C677T polymorphism of the methylenetetra hydrofolate reductase gene and its association with levels of serum homocysteine, folate, and vitamin B12 as maternal risk factors for Down syndrome

AIMS AND OBJECTIVE: Evaluation of C677T polymorphisms of the methylenetetra hydrofolate reductase (MTHFR) gene and its association with level of serum homocysteine, folate, and vitamin B12 as possible maternal risk factors for Down syndrome. DESIGN: This was a case–control study. MATERIAL AND METHOD...

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Detalles Bibliográficos
Autores principales: Mohanty, Pankaj K., Kapoor, Seema, Dubey, Anand P., Pandey, Sanjeev, Shah, Renuka, Nayak, Hemant K., Polipalli, Sunil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656515/
https://www.ncbi.nlm.nih.gov/pubmed/23716934
http://dx.doi.org/10.4103/0971-6866.107977