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Tau Pathology and Parietal White Matter Lesions Have Independent but Synergistic Effects on Early Development of Alzheimer's Disease

BACKGROUND: White matter lesions (WMLs) are a common finding in patients with dementia. This study investigates the relationship between WMLs, hyperphosphorylated tau (P-tau) in cerebrospinal fluid (CSF) and apolipoprotein E (APOE) ε4 genotype in prodromal Alzheimer's disease (AD). METHODS: Bas...

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Detalles Bibliográficos
Autores principales: Hertze, Joakim, Palmqvist, Sebastian, Minthon, Lennart, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656673/
https://www.ncbi.nlm.nih.gov/pubmed/23687506
http://dx.doi.org/10.1159/000348353