A Genetic Screen for High Copy Number Suppressors of the Synthetic Lethality Between elg1Δ and srs2Δ in Yeast

Elg1 and Srs2 are two proteins involved in maintaining genome stability in yeast. After DNA damage, the homotrimeric clamp PCNA, which provides stability and processivity to DNA polymerases and serves as a docking platform for DNA repair enzymes, undergoes modification by the ubiquitin-like molecule...

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Detalles Bibliográficos
Autores principales: Gazy, Inbal, Liefshitz, Batia, Bronstein, Alex, Parnas, Oren, Atias, Nir, Sharan, Roded, Kupiec, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Mutant Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656737/
https://www.ncbi.nlm.nih.gov/pubmed/23704284
http://dx.doi.org/10.1534/g3.113.005561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656737/
https://www.ncbi.nlm.nih.gov/pubmed/23704284
http://dx.doi.org/10.1534/g3.113.005561

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