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Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration

BACKGROUND: In Alzheimer’s disease, stroke and brain injuries, activated microglia can release proinflammatory cytokines, such as interleukin (IL)-1β. These cytokines may change astrocyte and neurotrophin functions, which influences neuronal survival and induces apoptosis. However, the interaction b...

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Detalles Bibliográficos
Autores principales: Song, Cai, Zhang, Ye, Dong, Yilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656796/
https://www.ncbi.nlm.nih.gov/pubmed/23651534
http://dx.doi.org/10.1186/1742-2094-10-59