Reversal of multidrug resistance by cisplatin-loaded magnetic Fe(3)O(4) nanoparticles in A549/DDP lung cancer cells in vitro and in vivo

The purpose of this study was to explore whether magnetic Fe(3)O(4) nanoparticles (Fe(3)O(4)-MNP) loaded with cisplatin (Fe(3)O(4)-MNP-DDP) can reverse DDP resistance in lung cancer cells and to investigate mechanisms of multidrug resistance in vitro and in vivo. MTT assay showed that DDP inhibited...

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Detalles Bibliográficos
Autores principales: Li, Ke, Chen, Baoan, Xu, Lin, Feng, Jifeng, Xia, Guohua, Cheng, Jian, Wang, Jun, Gao, Feng, Wang, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656817/
https://www.ncbi.nlm.nih.gov/pubmed/23690684
http://dx.doi.org/10.2147/IJN.S43752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656817/
https://www.ncbi.nlm.nih.gov/pubmed/23690684
http://dx.doi.org/10.2147/IJN.S43752

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