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Reversal of multidrug resistance by cisplatin-loaded magnetic Fe(3)O(4) nanoparticles in A549/DDP lung cancer cells in vitro and in vivo
The purpose of this study was to explore whether magnetic Fe(3)O(4) nanoparticles (Fe(3)O(4)-MNP) loaded with cisplatin (Fe(3)O(4)-MNP-DDP) can reverse DDP resistance in lung cancer cells and to investigate mechanisms of multidrug resistance in vitro and in vivo. MTT assay showed that DDP inhibited...
Autores principales: | Li, Ke, Chen, Baoan, Xu, Lin, Feng, Jifeng, Xia, Guohua, Cheng, Jian, Wang, Jun, Gao, Feng, Wang, Xuemei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656817/ https://www.ncbi.nlm.nih.gov/pubmed/23690684 http://dx.doi.org/10.2147/IJN.S43752 |
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