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Flurbiprofen benzyl nitrate (NBS-242) inhibits the growth of A-431 human epidermoid carcinoma cells and targets β-catenin

BACKGROUND: The Wnt/β-catenin/T cell factor (TCF) signaling pathway is important in the development of nonmelanoma skin cancers (NMSCs). Nitric-oxide-releasing nonsteroidal anti-inflammatory drugs (NO-NSAIDs) are chemopreventive agents consisting of a traditional NSAID attached to an NO-releasing mo...

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Detalles Bibliográficos
Autores principales: Nath, Niharika, Liu, Xiaoping, Jacobs, Lloydine, Kashfi, Khosrow
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656819/
https://www.ncbi.nlm.nih.gov/pubmed/23690679
http://dx.doi.org/10.2147/DDDT.S43771