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Decrypting Prion Protein Conversion into a β-Rich Conformer by Molecular Dynamics
[Image: see text] Prion diseases are fatal neurodegenerative diseases characterized by the formation of β-rich oligomers and the accumulation of amyloid fibrillar deposits in the central nervous system. Understanding the conversion of the cellular prion protein into its β-rich polymeric conformers i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656828/ https://www.ncbi.nlm.nih.gov/pubmed/23700393 http://dx.doi.org/10.1021/ct301118j |