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Decrypting Prion Protein Conversion into a β-Rich Conformer by Molecular Dynamics

[Image: see text] Prion diseases are fatal neurodegenerative diseases characterized by the formation of β-rich oligomers and the accumulation of amyloid fibrillar deposits in the central nervous system. Understanding the conversion of the cellular prion protein into its β-rich polymeric conformers i...

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Detalles Bibliográficos
Autores principales: Chakroun, Nesrine, Fornili, Arianna, Prigent, Stéphanie, Kleinjung, Jens, Dreiss, Cécile A., Rezaei, Human, Fraternali, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656828/
https://www.ncbi.nlm.nih.gov/pubmed/23700393
http://dx.doi.org/10.1021/ct301118j

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