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Inhibitory Neuron and Hippocampal Circuit Dysfunction in an Aged Mouse Model of Alzheimer's Disease

In Alzheimer's disease (AD), a decline in explicit memory is one of the earliest signs of disease and is associated with hippocampal dysfunction. Amyloid protein exerts a disruptive impact on neuronal function, but the specific effects on hippocampal network activity are not well known. In this...

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Detalles Bibliográficos
Autores principales: Hazra, Anupam, Gu, Feng, Aulakh, Ahmad, Berridge, Casey, Eriksen, Jason L., Žiburkus, Jokūbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656838/
https://www.ncbi.nlm.nih.gov/pubmed/23691195
http://dx.doi.org/10.1371/journal.pone.0064318