Simvastatin Inhibits Renal Cancer Cell Growth and Metastasis via AKT/mTOR, ERK and JAK2/STAT3 Pathway

Renal cell carcinoma (RCC) is the most lethal type of genitourinary cancer due to its occult onset and resistance to chemotherapy and radiation. Recently, accumulating evidence has suggested stains, inhibitors of 3-hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase, were associated with the ri...

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Detalles Bibliográficos
Autores principales: Fang, Zhiqing, Tang, Yueqing, Fang, Juanjuan, Zhou, Zunlin, Xing, Zhaoquan, Guo, Zhaoxin, Guo, Xiaoyu, Wang, Weichang, Jiao, Wei, Xu, Zhonghua, Liu, Zhaoxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656850/
https://www.ncbi.nlm.nih.gov/pubmed/23690956
http://dx.doi.org/10.1371/journal.pone.0062823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656850/
https://www.ncbi.nlm.nih.gov/pubmed/23690956
http://dx.doi.org/10.1371/journal.pone.0062823

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