miR-219-5p Inhibits Receptor Tyrosine Kinase Pathway by Targeting EGFR in Glioblastoma

Glioblastoma is one of the common types of primary brain tumors with a median survival of 12–15 months. The receptor tyrosine kinase (RTK) pathway is known to be deregulated in 88% of the patients with glioblastoma. 45% of GBM patients show amplifications and activating mutations in EGFR gene leadin...

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Detalles Bibliográficos
Autores principales: Rao, Soumya Alige Mahabala, Arimappamagan, Arivazhagan, Pandey, Paritosh, Santosh, Vani, Hegde, Alangar Sathyaranjandas, Chandramouli, Bangalore Ashwathnarayanara, Somasundaram, Kumaravel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656853/
https://www.ncbi.nlm.nih.gov/pubmed/23690991
http://dx.doi.org/10.1371/journal.pone.0063164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656853/
https://www.ncbi.nlm.nih.gov/pubmed/23690991
http://dx.doi.org/10.1371/journal.pone.0063164

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