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Elongated Membrane Tethers, Individually Anchored by High Affinity α(4)β(1)/VCAM-1 Complexes, Are the Quantal Units of Monocyte Arrests

The α(4)β(1) integrin facilitates both monocyte rolling and adhesion to the vascular endothelium and is physiologically activated by monocyte chemoattractant protein (MCP-1). The current study investigated the initial events in the adhesion of THP-1 cells to immobilized Vascular Cell Adhesion Molecu...

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Detalles Bibliográficos
Autores principales: Chu, Calvin, Celik, Emrah, Rico, Felix, Moy, Vincent T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656870/
https://www.ncbi.nlm.nih.gov/pubmed/23691169
http://dx.doi.org/10.1371/journal.pone.0064187