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Elongated Membrane Tethers, Individually Anchored by High Affinity α(4)β(1)/VCAM-1 Complexes, Are the Quantal Units of Monocyte Arrests
The α(4)β(1) integrin facilitates both monocyte rolling and adhesion to the vascular endothelium and is physiologically activated by monocyte chemoattractant protein (MCP-1). The current study investigated the initial events in the adhesion of THP-1 cells to immobilized Vascular Cell Adhesion Molecu...
Autores principales: | Chu, Calvin, Celik, Emrah, Rico, Felix, Moy, Vincent T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656870/ https://www.ncbi.nlm.nih.gov/pubmed/23691169 http://dx.doi.org/10.1371/journal.pone.0064187 |
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