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Hypoxia Stimulates the EMT of Gastric Cancer Cells through Autocrine TGFβ Signaling

Epithelial mesenchymal transition (EMT) is considered to be correlated with malignancy of cancer cells and responsible for cancer invasion and metastasis. We previously reported that distant metastasis was associated with hypoxia in gastric cancer. We therefore investigated the effect of hypoxic con...

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Detalles Bibliográficos
Autores principales: Matsuoka, Junko, Yashiro, Masakazu, Doi, Yosuke, Fuyuhiro, Yuhiko, Kato, Yukihiro, Shinto, Osamu, Noda, Satoru, Kashiwagi, Shinichiro, Aomatsu, Naoki, Hirakawa, Toshiki, Hasegawa, Tsuyoshi, Shimizu, Kiyoshi, Shimizu, Toshiyuki, Miwa, Atsushi, Yamada, Nobuya, Sawada, Tetsuji, Hirakawa, Kosei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656884/
https://www.ncbi.nlm.nih.gov/pubmed/23690936
http://dx.doi.org/10.1371/journal.pone.0062310