Thioridazine Induces Major Changes in Global Gene Expression and Cell Wall Composition in Methicillin-Resistant Staphylococcus aureus USA300

Subinhibitory concentrations of the neuroleptic drug thioridazine (TDZ) are well-known to enhance the killing of methicillin-resistant Staphylococcus aureus (MRSA) by β-lactam antibiotics, however, the mechanism underlying the synergy between TDZ and β-lactams is not fully understood. In the present...

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Detalles Bibliográficos
Autores principales: Thorsing, Mette, Klitgaard, Janne K., Atilano, Magda L., Skov, Marianne N., Kolmos, Hans Jørn, Filipe, Sérgio R., Kallipolitis, Birgitte H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656896/
https://www.ncbi.nlm.nih.gov/pubmed/23691239
http://dx.doi.org/10.1371/journal.pone.0064518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656896/
https://www.ncbi.nlm.nih.gov/pubmed/23691239
http://dx.doi.org/10.1371/journal.pone.0064518

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