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Thioridazine Induces Major Changes in Global Gene Expression and Cell Wall Composition in Methicillin-Resistant Staphylococcus aureus USA300

Subinhibitory concentrations of the neuroleptic drug thioridazine (TDZ) are well-known to enhance the killing of methicillin-resistant Staphylococcus aureus (MRSA) by β-lactam antibiotics, however, the mechanism underlying the synergy between TDZ and β-lactams is not fully understood. In the present...

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Detalles Bibliográficos
Autores principales:	Thorsing, Mette, Klitgaard, Janne K., Atilano, Magda L., Skov, Marianne N., Kolmos, Hans Jørn, Filipe, Sérgio R., Kallipolitis, Birgitte H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656896/ https://www.ncbi.nlm.nih.gov/pubmed/23691239 http://dx.doi.org/10.1371/journal.pone.0064518

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