Impact of High Glucose and Proteasome Inhibitor MG132 on Histone H2A and H2B Ubiquitination in Rat Glomerular Mesangial Cells

Background. Hyperglycemia plays a pivotal role in the development of diabetic nephropathy (DN) and may be related to epigenetic metabolic memory. One of the most crucial epigenetic mechanisms is histone modification, which is associated with the expression of a fibrosis factor in vascular injury. Ai...

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Detalles Bibliográficos
Autores principales: Gao, Chenlin, Chen, Guo, Liu, Li, Li, Xia, He, Jianhua, Jiang, Lan, Zhu, Jianhua, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657404/
https://www.ncbi.nlm.nih.gov/pubmed/23738337
http://dx.doi.org/10.1155/2013/589474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657404/
https://www.ncbi.nlm.nih.gov/pubmed/23738337
http://dx.doi.org/10.1155/2013/589474

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