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Resveratrol Impedes the Stemness, Epithelial-Mesenchymal Transition, and Metabolic Reprogramming of Cancer Stem Cells in Nasopharyngeal Carcinoma through p53 Activation

Cancer stem cells (CSCs) are able to self-renew and are refractory to cancer treatment. To investigate the effects of resveratrol on CSCs of nasopharyngeal carcinoma (NPC), we employed a behavior selection strategy to isolate CSCs based on radioresistance, chemoresistance, and tumor sphere formation...

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Detalles Bibliográficos
Autores principales: Shen, Yao-An, Lin, Chien-Hung, Chi, Wei-Hsin, Wang, Chia-Yu, Hsieh, Yi-Tao, Wei, Yau-Huei, Chen, Yann-Jang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657420/
https://www.ncbi.nlm.nih.gov/pubmed/23737838
http://dx.doi.org/10.1155/2013/590393