Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum

Advanced glycation end products (AGEs) might play a pathophysiological role in the development of diabetes and its complications. AGEs negatively affect pancreatic beta-cell function and the expression of transcriptional factors regulating insulin gene. Glucagon-like peptide-1 (GLP-1), an incretin h...

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Detalles Bibliográficos
Autores principales: Puddu, Alessandra, Sanguineti, Roberta, Durante, Arianna, Nencioni, Alessio, Mach, François, Montecucco, Fabrizio, Viviani, Giorgio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657444/
https://www.ncbi.nlm.nih.gov/pubmed/23737644
http://dx.doi.org/10.1155/2013/317120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657444/
https://www.ncbi.nlm.nih.gov/pubmed/23737644
http://dx.doi.org/10.1155/2013/317120

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