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Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum
Advanced glycation end products (AGEs) might play a pathophysiological role in the development of diabetes and its complications. AGEs negatively affect pancreatic beta-cell function and the expression of transcriptional factors regulating insulin gene. Glucagon-like peptide-1 (GLP-1), an incretin h...
Autores principales: | Puddu, Alessandra, Sanguineti, Roberta, Durante, Arianna, Nencioni, Alessio, Mach, François, Montecucco, Fabrizio, Viviani, Giorgio L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657444/ https://www.ncbi.nlm.nih.gov/pubmed/23737644 http://dx.doi.org/10.1155/2013/317120 |
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