Prevalence of K-RAS Codons 12 and 13 Mutations in Locally Advanced Head and Neck Squamous Cell Carcinoma and Impact on Clinical Outcomes

Background. RAS gene mutations have an impact on treatment response and overall prognosis for certain types of cancer. Objectives. To determine the prevalence and impact of K-RAS codons 12 and 13 mutations in patients with locally advanced HNSCC treated with primary or adjuvant chemo-radiation. Meth...

Descripción completa

Detalles Bibliográficos
Autores principales: Bissada, Eric, Abboud, Olivier, Abou Chacra, Zahi, Guertin, Louis, Weng, Xiaoduan, Nguyen-Tan, Phuc Félix, Tabet, Jean-Claude, Thibaudeau, Ève, Lambert, Louise, Audet, Marie-Lise, Fortin, Bernard, Soulières, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657450/
https://www.ncbi.nlm.nih.gov/pubmed/23737793
http://dx.doi.org/10.1155/2013/848021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657450/
https://www.ncbi.nlm.nih.gov/pubmed/23737793
http://dx.doi.org/10.1155/2013/848021

Ejemplares similares