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Subthalamic hGAD65 Gene Therapy and Striatum TH Gene Transfer in a Parkinson’s Disease Rat Model

The aim of the present study is to detect a combination method to utilize gene therapy for the treatment of Parkinson’s disease (PD). Here, a PD rat model is used for the in vivo gene therapy of a recombinant adeno-associated virus (AAV2) containing a human glutamic acid decarboxylase 65 (rAAV2-hGAD...

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Detalles Bibliográficos
Autores principales: Zheng, Deyu, Jiang, Xiaohua, Zhao, Junpeng, Duan, Deyi, Zhao, Huanying, Xu, Qunyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657459/
https://www.ncbi.nlm.nih.gov/pubmed/23738148
http://dx.doi.org/10.1155/2013/263287