Cytochrome P450 (CYP2C9*2,*3) & vitamin-K epoxide reductase complex (VKORC1 -1639G<A) gene polymorphisms & their effect on acenocoumarol dose in patients with mechanical heart valve replacement

BACKGROUND & OBJECTIVES: Studies have demonstrated the effect of CYP2C9 (cytochrome P450) and VKORC1 (vitamin K epoxide reductase complex) gene polymorphisms on the dose of acenocoumarol. The data from India about these gene polymorphisms and their effects on acenocoumarol dose are scarce. The a...

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Detalles Bibliográficos
Autores principales: Kaur, Anupriya, Khan, Farah, Agrawal, Suraksha S., Kapoor, Aditya, Agarwal, Surendra K., Phadke, Shubha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657889/
https://www.ncbi.nlm.nih.gov/pubmed/23481074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657889/
https://www.ncbi.nlm.nih.gov/pubmed/23481074

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