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Determination of deflazacort in human plasma by liquid chromatography-mass spectrometry after liquid-liquid extraction and its application in human pharmacokinetics studies

PURPOSE: A sensitive liquid chromatography-mass spectrometric (LC/MS) has been developed and validated for the quantification of deflazacort in human plasma after liquid-liquid extraction (LLE). MATERIALS AND METHODS: Best chromatographic resolution was achieved on a reverse-phase Phenomenex C(18) c...

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Detalles Bibliográficos
Autores principales: Selvadurai, Muralidharan, Meyyanathan, Subramania Nainar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658040/
https://www.ncbi.nlm.nih.gov/pubmed/23781439
http://dx.doi.org/10.4103/2229-4708.84450