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A simple and rapid high-performance liquid chromatographic method for determining tobramycin in pharmaceutical formulations by direct UV detection

BACKGROUND: Tobramycin, an aminoglycoside antibiotic, is a polar pharmaceutical compound which lacks a UV absorbing chromophore. Due to the absence of a UV absorbing chromophore and high polar nature of this antibiotic, the analysis of such compounds becomes a major challenge. OBJECTIVE: To overcome...

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Detalles Bibliográficos
Autores principales: Ruckmani, K., Shaikh, Saleem Z., Khalil, Pavne, Muneera, M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658043/
https://www.ncbi.nlm.nih.gov/pubmed/23781441
http://dx.doi.org/10.4103/2229-4708.84455