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Estimation of sertraline by chromatographic (HPLC-UV(273 nm)) technique under hydrolytic stress conditions

PURPOSE: In this paper, simple, specific and accurate RP-HPLC method was developed in order to study decomposition of sertraline (SRT) under the hydrolytic stress conditions (acid, neutral, alkaline and oxidative). MATERIALS AND METHODS: The best separation of SRT and its degradation products were a...

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Detalles Bibliográficos
Autores principales: Rahman, Md. Akhlaquer, Iqbal, Zeenat, Mirza, Mohd. Aamir, Hussain, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658087/
https://www.ncbi.nlm.nih.gov/pubmed/23781480
http://dx.doi.org/10.4103/2229-4708.103874