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Greatwall kinase and cyclin B-Cdk1 are both critical constituents of M-phase-promoting factor

Maturation/M-phase-promoting factor is the universal inducer of M-phase in eukaryotic cells. It is currently accepted that M-phase-promoting factor is identical to the kinase cyclin B–Cdk1. Here we show that cyclin B–Cdk1 and M-phase-promoting factor are not in fact synonymous. Instead, M-phase-prom...

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Detalles Bibliográficos
Autores principales: Hara, Masatoshi, Abe, Yusuke, Tanaka, Toshiaki, Yamamoto, Takayoshi, Okumura, Eiichi, Kishimoto, Takeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658099/
https://www.ncbi.nlm.nih.gov/pubmed/22968705
http://dx.doi.org/10.1038/ncomms2062