Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish

Mutations in the transactive response DNA binding protein-43 (TARDBP/TDP-43) gene, which regulates transcription and splicing, causes a familial form of amyotrophic lateral sclerosis (ALS). Here, we characterize and report the first tardbp mutation in zebrafish, which introduces a premature stop cod...

Descripción completa

Detalles Bibliográficos
Autores principales: Hewamadduma, Channa A.A., Grierson, Andrew J., Ma, Taylur P., Pan, Luyuan, Moens, Cecilia B., Ingham, Philip W., Ramesh, Tennore, Shaw, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658164/
https://www.ncbi.nlm.nih.gov/pubmed/23427147
http://dx.doi.org/10.1093/hmg/ddt082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658164/
https://www.ncbi.nlm.nih.gov/pubmed/23427147
http://dx.doi.org/10.1093/hmg/ddt082

Ejemplares similares