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Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding

In pharmacology, it is crucial to understand the complex biological responses that drugs elicit in the human organism and how well they can be inferred from model organisms. We therefore identified a large set of drug-induced transcriptional modules from genome-wide microarray data of drug-treated h...

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Detalles Bibliográficos
Autores principales: Iskar, Murat, Zeller, Georg, Blattmann, Peter, Campillos, Monica, Kuhn, Michael, Kaminska, Katarzyna H, Runz, Heiko, Gavin, Anne-Claude, Pepperkok, Rainer, van Noort, Vera, Bork, Peer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658274/
https://www.ncbi.nlm.nih.gov/pubmed/23632384
http://dx.doi.org/10.1038/msb.2013.20