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Role of Calcium Channels in Heavy Metal Toxicity

The role of voltage-dependent Ca channels (VDCC) in the membrane permeation of two toxic metals, lead (Pb) and cadmium (Cd), was studied in mammalian cells. Both metals interact with Ca-binding sites, but, while Cd influx appears to occur mainly through the same pathways as Ca, Pb is also rapidly ta...

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Detalles Bibliográficos
Autor principal: Marchetti, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658387/
https://www.ncbi.nlm.nih.gov/pubmed/23724297
http://dx.doi.org/10.1155/2013/184360