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Low expression of the putative tumour suppressor spinophilin is associated with higher proliferative activity and poor prognosis in patients with hepatocellular carcinoma

BACKGROUND: Spinophilin, a multifunctional intracellular scaffold protein, is reduced in certain types of cancer and is regarded as a novel putative tumour suppressor protein. However, the role of spinophilin in hepatocellular carcinoma (HCC) has never been explored before. METHODS: In this study, w...

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Detalles Bibliográficos
Autores principales: Aigelsreiter, A, Ress, A L, Bettermann, K, Schauer, S, Koller, K, Eisner, F, Kiesslich, T, Stojakovic, T, Samonigg, H, Kornprat, P, Lackner, C, Haybaeck, J, Pichler, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658515/
https://www.ncbi.nlm.nih.gov/pubmed/23591196
http://dx.doi.org/10.1038/bjc.2013.165