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LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor

In baseball parlance, a triple threat is a person who can run, hit and throw with aplomb. Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a cell surface protein that antagonises ERBB receptor signalling by downregulating receptor levels. Over 10 years ago, Hedman et al postulated t...

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Detalles Bibliográficos
Autores principales: Wang, Y, Poulin, E J, Coffey, R J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658528/
https://www.ncbi.nlm.nih.gov/pubmed/23558895
http://dx.doi.org/10.1038/bjc.2013.138