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LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor
In baseball parlance, a triple threat is a person who can run, hit and throw with aplomb. Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a cell surface protein that antagonises ERBB receptor signalling by downregulating receptor levels. Over 10 years ago, Hedman et al postulated t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658528/ https://www.ncbi.nlm.nih.gov/pubmed/23558895 http://dx.doi.org/10.1038/bjc.2013.138 |