Fluorescent Ligand for Human Progesterone Receptor Imaging in Live Cells

[Image: see text] We employed molecular modeling to design and then synthesize fluorescent ligands for the human progesterone receptor. Boron dipyrromethene (BODIPY) or tetramethylrhodamine were conjugated to the progesterone receptor antagonist RU486 (Mifepristone) through an extended hydrophilic l...

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Detalles Bibliográficos
Autores principales: Weinstain, Roy, Kanter, Joan, Friedman, Beth, Ellies, Lesley G., Baker, Michael E., Tsien, Roger Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658552/
https://www.ncbi.nlm.nih.gov/pubmed/23600997
http://dx.doi.org/10.1021/bc3006418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658552/
https://www.ncbi.nlm.nih.gov/pubmed/23600997
http://dx.doi.org/10.1021/bc3006418

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